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Doctors tout the
benefits of Poly-MVA
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James W. Forsythe
M.D., H.M.D.
Board Certified Oncologist
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One of the Doctors
Featured in Suzanne Somers' new Book, Knockout.
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Poly-MVA: Quality of LIfe Study
Dr. Forsythe performed a Poly-MVA
outcome-based investigation with 212
patients over a 2.5 year period
on various (18 types) Stage IV
Cancers , in which he observed
a 56 % overall positive response
rate. Dr. Forsythe found that
Poly-MVA is a safe and highly effective supplement for palliative assistance in Stage IV cancer patients. |
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Dr. Forsythe Video
Time: 3min 48sec 
Click above to watch video
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Burton Goldberg
Author & Editor of
18 books on
Alternative Medicine
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One of the Researchers Featured in Suzanne
Somers' new Book, Knockout.
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Excerpt from "An Alternative Medicine Definitive Guide to Cancer"
"A major factor in the success of Poly-MVA has been to provide an electron energy transfer mechanism from
normal metabolic hydrogen carriers to nucleic acids while at the same time protecting DNA and RNA [ribonucleic
acid] as a result of the new reduced state it induces in the nucleotides."
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Jeffrey Mueller M.D.
Director of Integrative Health
Programs |
| "Poly MVA has become the foundation of our
combined approach because of our experience using Poly MVA with stage III and IV cancers has been extremely promising.
What we are seeing is a synergy between Poly MVA, advanced nutritional protocols, and conventional aproaches. We
have seen patients go into full remission with aggressive, stage IV cancers that have metastasized, and we see
continued positive responses in others with previously chemo-resistant cancers.The other benefit, that we have
seen with this approach, is a significantly improved quality of life and a substantial reduction in the number
and severity of side effects from chemo and radiation therapies." |
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Robert D. Milne, MD
Milne Medical Center in Las Vegas, Nevada |
| "Based on my father-in-law's excellent result
and the results experienced by many others, I truly believe that Poly-MVA is worth trying by any person who has
cancer." |
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David C. Korn, D.D.S., D.O., M.D.(H).
LongLife Medical Incorporated in Mesa,
Arizona |
| “Not until I used Poly-MVA, did I believe and
understand how remarkable and powerful it is. Everyone involved with Poly-MVA are genuine people trying to help
others.” |
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Francis J. Antonawich Ph.D.
Assistant Professor of Neurology-Stony
Brook
University |
| "Poly MVA is a dietary supplement based on
the success of Lipoic Acid Palladium (LAPd) complex. LAPd is a liquid crystal that works in our cells by transferring
excess electrons (energy) from membrane fatty acids to DNA via the mitochondria. Therefore, by its structural nature
and action as a redox shuttle, it can both quench radicals as well as provide energy to the mitochondria. |
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Exclusive Distributor of Poly-MVA
Speak to a Poly-MVA Consultant
Available Monday thru Friday
from
8 AM to 5 PM Pacific Standard Time.
Call Toll Free
1-866-765-9682
www.PolyMVA.com
John Fox
LUNG CANCER
"The people at AMARC have been
incredible, passionate, and very knowledgable - without them I am sure I would not be working in the Fire Department
today. They put their hearts in what they do and help save lives everyday! Thank you AMARC for all you do! "
Gary & Elma Thomas
SQUAMOUS CELL CARINOMA
PROSTATE CANCER
"I am quite sure without Poly-MVA
to support our bodies, neither my wife nor I would be here to tell you this story. Thank you, Poly-MVA, and to
the wonderful AMARC staff - you have blessed our lives."
Michael Muscari
PROSTATE CANCER
"Thank you! Thank you! Thank
you! You all are our heroes! Gary, Dr. Llamas, Al Jr, Linda and all of the terrific people at AMARC are heroes
and living angels in our lives."
Bernie Kanter
BLADDER CANCER
"Thank you to AMARC for having
an excellent product, and for being available to us.” |
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5 Clinical Studies supporting the use of Antioxidants
during Chemotherapy & Radiation
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Should Antioxidants be used with Chemo and
Radiation?
There is a lot of confusion surrounding this issue, and the
advice coming out of many medical institutions is based on the belief that antioxidants may interfere with the
chemotherapeutic effect on cancer tissue.
Dr. Charles B. Simone believes that most of this bad
press came from a New York Times article in 1997
in which two physicians from a prominent cancer center "told cancer patients not to take antioxidants and other vitamins while receiving chemotherapy
and radiation therapy. The entire oncology community took the same position without ever reviewing the evidence
- and passed the misinformation along to their patients."
However, recently released clinical studies (2007, 2008 and 2009) strongly demonstrate that the use of antioxidant supplements during chemotherapy and radiation is in fact safe
and often enhances the effectiveness of each
modality.
Click on the link at the bottom of the page to see 5 clinical studies that support antioxidant use during any form
of Conventional Cancer treatment.
Article #2 details an extensive review of 280
peer-reviewed articles (based on 62 in vitro
and 218 in vivo independent studies) which stated, "antioxidants
and other nutrients enhance and support the body in dealing with cancer, decrease their side effects, and protect
normal tissue."
Several of the studies that were reviewed showed, "the
antioxidant group completed more full doses of chemotherapy or had less-dose reduction than control groups." Therefore, the addition of Poly-MVA as an adjunct during Chemotherapy
and Radiation regimens might assist in sustaining the overall well being of each patient and allow Oncologists and Radiologists a better opportunity to complete
their entire Chemotherapy and Radiation protocols.
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ATTENTION CANCER PATIENTS!
Print out these articles and
share them with your Doctor!
1/3 of Cancer Patients
Quit treatment due to Toxicity
Shrinking tumors and lengthening lives is of course what
cancer treatment is all about, but don't underestimate
the importance of reducing side effects and maintaining a good quality of life. After all, fewer ill effects mean fewer patients forego their prescribed chemotherapy regimens.
When patients get sick from chemotherapy, their
regimens often are interrupted - either on
their doctors' orders or because they choose to stop following them. In fact, toxic side effects lead as many as one-third
of cancer patients to abandon treatment altogether.
Both common sense and existing research tell us that by reducing dosing and interrupting or diminishing a patient's
chemotherapy schedule, the efficacy of the treatment - and therefore the outcome - is diminished.
"The potential for antioxidants to reduce
chemotherapy side effects is the larger issue behind our research," stated 1 of the authors. "Fewer
side effects mean more patients will complete their prescribed regimens at the full recommended dosages and on
schedule."
"We believe the research suggests that antioxidants can not only diminish toxicity, they can
improve outcomes in terms of tumor response, survival
rates, and treatment tolerance."
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Poly-MVA ORAC ANALYSIS
As you are reading the 5 Clinical Studies below, pay
close attention to the list of Antioxidants that demonstrated substantial clinical benefit. It is important to understand the superiority of Poly-MVA's liquid
cyrstal polymer when compared to these standard vitamins and compounds.
Data suggests that polymers like Poly-MVA have
greater antioxidant potential than monomolecular structures like vitamins. Any monomolecular antioxidant absorbs electrons, but it also donates them, acting as a pro-oxidant.
Dr. Garnett’s electrochemistry papers demonstrate that the lipoic acid–palladium compound(Poly-MVA) has far better
antioxidant potential than any other vitamin tested.
Dr. Antonawich sent samples of Palladium Lipoic Complex to Brunswick Laboratories in Wareham, Massachusetts, for an ORAC analysis, which measures the ability of a substance to absorb free radicals
in comparison to other vitamins.
The results were pretty stunning, as expressed in vitamin E equivalents per gram:
Vitamin A = 1.6
Melatonin = 2.04
Vitamin C = 1.12
Lipoic Acid = 1.4
Vitamin E = 1.0
Poly-MVA (Palladium Lipoic Complex)
= 5.65
ATTENTION CANCER PATIENTS
Click on the PDF icon below and print all 5 studies
Provide these reports to your Doctor/Oncologist
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Clinical Studies supporting the use of Antioxidants
during Chemotherapy and Radiation
5 Published Articles
Each article can be found
online at the
National Institutes of Health website.
Click below
PubMed.gov live link
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Article 1
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1: Int J Cancer. 2008 Sep 15;123(6):1227-39.
Impact of antioxidant supplementation
on chemotherapeutic toxicity: a systematic review of the evidence from randomized controlled trials.
Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal C.
Institute for Integrative Cancer Research and Education, Suite 350, Evanston, IL, USA.
Much debate has focused on whether antioxidants interfere with the efficacy of cancer chemotherapy. The objective
of this study is to systematically review the randomized, controlled clinical trial evidence evaluating the effects
of concurrent use of antioxidants with chemotherapy on toxic side effects.
We performed a search of literature from 1966-October 2007 using MEDLINE, Cochrane, CinAhl, AMED, AltHealthWatch
and EMBASE databases. Randomized, controlled clinical trials reporting antioxidant-based mitigation of chemotherapy
toxicity were included in the final tally. Searches were performed following a standardized protocol for systematic
reviews. Only 33 of 965 articles considered, including 2,446 subjects, met the inclusion criteria. Antioxidants evaluated were: glutathione (11), melatonin
(7), vitamin A (1), an antioxidant mixture (2), N-acetylcysteine (2), vitamin E (5), selenium (2), L-carnitine
(1), Co-Q10 (1) and ellagic acid (1).
The majority (24) of the 33 studies
included reported evidence of decreased toxicities from the concurrent use of antioxidants with chemotherapy. Nine studies reported no difference in toxicities between
the 2 groups. Only 1 study (vitamin A) reported a significant increase in toxicity in the antioxidant group. Five studies reported the antioxidant group completed
more full doses of chemotherapy or had less-dose reduction than control groups. Statistical power and poor study quality were concerns with some studies.
This review provides the first
systematically reviewed evidence that antioxidant supplementation during chemotherapy holds potential for reducing
dose-limiting toxicities. However,
well-designed studies evaluating larger populations of patients given specific antioxidants defined by dose and
schedule relative to chemotherapy are warranted.
QUOTES FROM AUTHORS
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DR. ROBERT NEWMAN
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Co-author Dr. Robert Newman, Professor of
Cancer Medicine at M. D. Anderson Cancer Center said, “This study, along with the evolving understanding of antioxidant-chemotherapy interactions,
suggests that the previously held beliefs about interference do not pertain to clinical treatment.” |
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KEITH BLOCK, MD
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“This review demonstrates that there is no scientific
support for the blanket objection to using antioxidants during chemotherapy. In addition, it also appears that these supplements may help mitigate the side effects of chemotherapy,” said Keith I. Block, MD, lead author of the study and Medical Director of the Block Center for Integrative Cancer Treatment.
“This is significant because it
increases the likelihood that patients will be able to complete their treatment.” |
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Article 2
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1: Altern Ther Health Med. 2007 Mar-Apr;13(2):40-7.
Links
Antioxidants and other nutrients do not
interfere with chemotherapy or radiation therapy and can increase kill and increase survival, Part 2.
Simone CB 2nd, Simone NL, Simone V, Simone CB.
Simone Protective Cancer Institute in Lawrenceville, NJ, USA.
PURPOSE: Some in the oncology community contend that patients undergoing chemotherapy and/or radiation therapy
should not use food supplement antioxidants and other nutrients. Oncologists at an influential oncology institution
contended that antioxidants interfere with radiation and some chemotherapies because those modalities kill by generating
free radicals that are neutralized by antioxidants, and that folic acid interferes with methotrexate. This is despite
the common use of amifostine and dexrazoxane, 2 prescription antioxidants, during chemotherapy and/or radiation
therapy.
DESIGN: To assess all evidence concerning antioxidant and other nutrients used concomitantly with chemotherapy
and/or radiation therapy. The MEDLINE and CANCERLIT databases were searched from 1965 to November 2003 using the
words vitamins, antioxidants, chemotherapy, and radiation therapy. Bibliographies of articles were searched. All
studies reporting concomitant nutrient use with chemotherapy and/or radiation therapy (280 peer-reviewed articles including 62 in vitro and 218 in vivo) were indiscriminately included.
RESULTS: Fifty human clinical randomized or observational trials have been conducted, involving 8,521 patients
using beta-carotene; vitamins A, C, and E; selenium; cysteine; B vitamins; vitamin D3; vitamin K3; and glutathione
as single agents or in combination.
CONCLUSIONS: Since the 1970s, 280 peer-reviewed
in vitro and in vivo studies, including 50 human studies involving 8,521 patients, 5,081 of whom were given nutrients, have consistently shown that antioxidants do not interfere
with therapeutic modalities for cancer. Furthermore,
non-prescription antioxidants and other nutrients enhance the killing of therapeutic modalities for cancer, decrease
their side effects, and protect normal tissue.
In 15 human studies, 3,738 patients who took
non-prescription antioxidants and other nutrients actually had increased survival.
QUOTE FROM AUTHOR
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CHARLES SIMONE, M.D.
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"If your doctor tells you not to take antioxidant
supplements or nutrients during your treatment, ask him or her to show you the rationale for this decision from
a peer-reviewed journal," Simone says. "It cannot be produced because there isn't any."
The bottom line, he says, is that "our
study shows that millions of
cancer patients who receive chemotherapy and/or radiation therapy should take antioxidants and other nutrients because there is no interference, there is greater cancer destruction, there are fewer
side effects, and about two-thirds of the patients live longer." |
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Article 3
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1: Cancer Treat Rev. 2007 Aug;33(5):407-18. Epub 2007
Mar 23.
Impact of antioxidant supplementation
on chemotherapeutic efficacy: a systematic review of the evidence from
randomized controlled trials.
Block KI, Koch AC, Mead MN, Tothy PK, Newman RA, Gyllenhaal
C.
Institute for Integrative Cancer Research and Education, 1800 Sherman Avenue, Suite 350, Evanston, IL 60201, USA.
PURPOSE: Much debate has arisen about whether
antioxidant supplementation alters the efficacy of cancer chemotherapy. Some have argued that antioxidants scavenge
the reactive oxygen species integral to the activity of certain chemotherapy drugs, thereby diminishing treatment
efficacy. Others suggest antioxidants may mitigate toxicity and thus allow for uninterrupted treatment schedules
and a reduced need for lowering chemotherapy doses. The objective of this study is to systematically review the
literature in order to compile results from randomized trials that evaluate concurrent use of antioxidants with
chemotherapy.
DESIGN: MEDLINE, Cochrane, CinAhl, AMED, AltHealthWatch and EMBASE databases were searched. Only randomized,
controlled clinical trials that reported survival and/or tumor response were included in the final tally. The literature
searches were performed in duplicate following a standardized protocol. No meta-analysis was performed due to heterogeneity
of tumor types and treatment protocols used in trials that met the inclusion criteria.
RESULTS: Of 845 articles considered,
19 trials met the inclusion criteria. Antioxidants evaluated were: glutathione (7), melatonin (4), vitamin A (2), an antioxidant mixture (2), vitamin C (1), N-acetylcysteine
(1), vitamin E (1) and ellagic acid (1). Subjects of most studies had advanced or relapsed disease.
CONCLUSION: None of the trials reported evidence of significant decreases in efficacy from antioxidant supplementation
during chemotherapy. Many of the studies indicated
that antioxidant supplementation resulted in either increased survival times, increased tumor responses, or both,
as well as fewer toxicities than controls;
however, lack of adequate statistical power was a consistent limitation. Large, well-designed studies of antioxidant
supplementation concurrent with chemotherapy are warranted.
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Article 4
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1: Radiat Res. 2009 Aug;172(2):175-86. Links
Protective effects of dietary antioxidants
on proton total-body irradiation-mediated hematopoietic cell and animal survival.
Wambi CO, Sanzari JK, Sayers CM, Nuth M, Zhou Z, Davis J,
Finnberg N, Lewis-Wambi JS, Ware JH, El-Deiry WS, Kennedy AR.
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
Abstract: Dietary antioxidants have radioprotective
effects after gamma-radiation exposure that limit hematopoietic cell depletion and improve animal survival. The purpose of this study was to determine whether a dietary supplement
consisting of l-selenomethionine, vitamin C, vitamin E succinate, alpha-lipoic acid and N-acetyl
cysteine could improve survival of mice after proton total-body irradiation (TBI).
Antioxidants significantly increased 30-day
survival of mice only when given after irradiation at a dose less than the calculated LD(50/30); for these data, the dose-modifying factor (DMF) was 1.6. Pretreatment
of animals with antioxidants resulted in significantly
higher serum total white blood cell, polymorphonuclear cell and lymphocyte cell counts at 4 h after 1 Gy but not 7.2 Gy proton TBI.
Antioxidants significantly modulated plasma
levels of the hematopoietic cytokines Flt-3L and TGFbeta1 and increased bone marrow cell counts and spleen mass
after TBI. Maintenance of the antioxidant
diet resulted in improved recovery of peripheral
leukocytes and platelets after sublethal and potentially lethal TBI. Taken together, oral supplementation
with antioxidants appears to be an effective approach for radioprotection of hematopoietic cells and improvement
of animal survival after proton TBI.
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Article 5
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1: Radiat Res. 2008 Apr;169(4):384-96. Links
Dietary antioxidants protect hematopoietic
cells and improve animal survival after total-body irradiation.
Wambi C, Sanzari J, Wan XS, Nuth M, Davis J, Ko YH, Sayers
CM, Baran M, Ware JH, Kennedy AR.
Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA.
The purpose of this study was to determine whether a dietary supplement consisting of L-selenomethionine, vitamin
C, vitamin E succinate, alpha-lipoic acid and N-acetyl cysteine could improve the survival of mice after total-body
irradiation.
Antioxidants significantly increased the 30-day
survival of mice after exposure to a potentially lethal dose of X rays when given prior to or after animal irradiation.
Pretreatment of animals with antioxidants resulted in significantly higher total white blood cell
and neutrophil counts in peripheral blood
at 4 and 24 h after 1 Gy and 8 Gy. Antioxidants
were effective in preventing peripheral lymphopenia only after low-dose irradiation. Antioxidant supplementation was also associated
with increased bone marrow cell counts after irradiation.
Supplementation with antioxidants was associated
with increased Bcl2 and decreased Bax, caspase 9 and TGF-beta1 mRNA expression in the bone marrow after irradiation.
Maintenance of the antioxidant diet was associated with improved recovery of the bone marrow after sublethal
or potentially lethal irradiation.
Taken together, oral supplementation with antioxidants
appears to be an effective approach for radioprotection of hematopoietic cells and improvement of animal survival,
and modulation of apoptosis is implicated
as a mechanism for the radioprotection of the hematopoietic system by antioxidants.
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